医生 安娜玛丽•罗素教授
领域 生化学
• Pharmacien, Docteur en Pharmacie, Docteur ès Sciences
• Professeur Émérite des Universités
• Discipline Biochimie Générale, Métabolique et Nutritionnelle Université Grenoble Alpes
课程:临床生理营养学
介绍
临床生理营养是一门学科,包括临床研究、生理学、生物学研究以及宏观和微量营养素不平衡的管理,同时考虑到它们的协同作用及其相互作用。我们身体的11种基本平衡水平中的作用,即膳食平衡、微生物群平衡、肠道通透性平衡、排毒平衡、氧化 – 炎症平衡、必需脂肪酸平衡、酸碱平衡、神经介质平衡、线粒体平衡、代谢和激素平衡、心理 – 行为平衡。此外,临床生理营养包含了前沿的学科,比如:荷尔蒙营养。
目标
① 提供真正的临床生理营养学咨询。
② 采用有科学依据的问卷调查为患者提供营养学、微营养学和内分泌方面的咨询。
③ 制定个性化营养和微营养管理计划。
视频
课程
学术论文
1994年10⽉份, 法国政府⼀次国家的⼤型的营养补充调查: “ SU.VI.MAX. ”. 由法国卫⽣局制定 Serge Hercberg医⽣负责。 该研究从1994年开始⼀直到2003年,历时8年。总共有13017位男性和⼥性,⼀组摄⼊每⽇摄⼊维C、维E、胡萝卜素、锌、以及硒。 结论发现: 通过每⽇摄⼊抗氧化微量元素,癌症发病率降低31%,意外伤亡降低37%。
该研究的微量元素定性,定量,以及效果跟踪是由格勒诺布尔⼤学⽣化系负责,安娜玛丽·罗素教授 也是团队负责⼈之⼀。
安娜玛丽·罗素教授作为欧洲首批研究生理营养以及微量元素的科学家,从微量元素到细胞能量系列产品的摄取,对妇⼥,对⽼年⼈,对⾼⽔平运动员,对病理性都有深入研究研究, 并在营养学、临床医学、病理学等各领域发表了大量论文。
Stress exposure alters brain mRNA expression of the genes involved in insulin signalling, an effect modified by a high fat/high fructose diet and cinnamon supplement⾼糖⾼脂饮⻝下压⼒通过胰岛素反应对脑部mRNA(单链核糖核酸) 基因表达的改变
POLS ONE – 05/2018
Frederic Canini / Bolin Qin / Anne Marie ROUSSEL 等多位
Positive effects of an oral supplementation by Glisodin, a gliadin-combined SOD rich melon extract, in an animal model of dietary-induced oxidative stress
⼝服Gliosdin (⼀种法国甜⽠(Cucumis melo)中提取的超氧化歧化酶 (Superoxide Dismutase; SOD)由⼩⻨胶原蛋⽩(Gliadin)的⽣物⾼聚物包裹构成)动物实验上对降低氧化压⼒的有效帮助
Nutrition – 02/2015
Isabelle Hininger / M. Osman / Anne-Marie Roussel等多位
Acute stress delays brain mitochondrial permeability transition pore opening Article
压⼒对脑部线粒体的渗透性开⼝的影响
Journal of neurochemistry – 07/2014
Cecile Batandier / Laurent Poulet / Anne Marie ROUSSEL / 等多位
Trace elements (zinc, selenium, chromium, iron), metabolic syndrome, and type 2 diabetes
微量元素(锌,硒,铬,铁)在代谢类疾病、⼆型糖尿病的表达
Médecine des Maladies Métaboliques-01/2014
Anne-Marie Roussel
Cinnamon Counteracts the Negative Effects of a High Fat/High Fructose Diet on Behavior, Brain Insulin Signaling and Alzheimer-Associated Changes
⾁桂对⾼脂肪和⾼糖餐饮影响,脑部胰岛素信号和阿尔兹海默症的改变
Jounal of POLS online – 12/2013
Richard A Anderson / Bolin Qin /Laurent Poulet / Anne-Marie Roussel等多位
Effects of a high-fat–high-fructose diet, stress and cinnamon on central expression of genes related to immune system, hypothalamic–pituitary–adrenocortical axis function and cerebral plasticity in rats
⾼脂⾼糖饮⻝,压⼒以及⾁桂对免疫系统基因表达的影响,⼩⽩鼠脑下丘-脑垂体-肾上腺功能和脑部塑形模型
British Journal of Nutrition – 11/2013
Nathalie Marissal-Arvy / Cecile Batandier / Anne Marie ROUSSEL – 等多位作者
Micronutrient status and cognitive decline in ageing
微量元素对衰⽼过程中认知能⼒下降的影响
European Geriatric Medicine – 02/2011
Monique Ferry / Anne-Marie Roussel
Chrome et syndrome métabolique: Chromium and the metabolic syndrome
铬元素对代谢病理的影响
Médecine des Maladies Métaboliques – 11/2009
Anne-Marie Roussel
Micronutrient status and cognitive decline in ageing
微量元素对衰⽼过程中认知能⼒下降的影响
European Geriatric Medicine – 02/2011
Monique Ferry / Anne-Marie Roussel
Green Tea Extract Decreases Oxidative Stress and Improves Insulin Sensitivity in an Animal Model of Insulin Resistance, the Fructose-Fed Rat
⼩⽩⿏⾼脂肪胰岛素模型 :茶叶提取降低氧化危害改善胰岛敏感度
Journal of the American College of Nutrition – 08/2009
Isabelle Hininger / Rachida Benaraba / Sara Coves / Anne-Marie Roussel
Antioxidant Effects of a Cinnamon Extract in People with Impaired Fasting Glucose That Are Overweight or Obese
⾁桂的抗氧化能⼒在治疗超重超胖病⼈上的⽐较
Journal of the American College of Nutrition – 03/ 2009
Anne-Marie Roussel / Isabelle Hininger / Rachida Benaraba / Richard A Anderson 等多位
Zinc supplementation does not alter plasma homocysteine, vitamin B12 and red blood cell folate concentrations in French elderly subjects
法国⽼年⼈群锌摄⼊对⾎浆中同型半胱氨酸,维⽣素B12以及红细胞中天然叶酸的影响
Journal of Trace Elements in Medicine and Biology – 01/ 2009
Véronique Ducros / Maud Andriollo / Josiane Arnaud/ Anne-Marie Roussel
Fibrates but not statins increase plasma selenium in dyslipidemic aged patients – The EVA study
⻉丁酸类降脂药(Fibrate) ,⾮他汀类药物增加⾎脂异常⽼年⼈的⾎浆中的硒含量
(EVA-Etude du viellissment Arteriel ) – 01/2009
Josiane Arnaud / Tasnime Akbaraly / Isabelle Hininger / Anne-Marie Roussel
Relationships between selenium, lipids, iron status and hormonal therapy in women of the SU.VIMAX cohort
硒元素,脂肪,铁元素和⼥性荷尔蒙治疗的关系
Journal of Trace Elements in Medicine and Biology 12/ 2007
Josiane Arnaud / Anne-Marie Roussel/ Serge Hercberg 等多位
Effect of Low Dose Antioxidant Vitamin and Trace Element Supplementation on the Urinary Concentrations of Thromboxane and Prostacyclin Metabolites
低剂量抗氧化剂和微量元素补充在尿液中前列环素和⾎栓素B2的变化
Journal of American College Nutrition – 11/2007
Josiane Arnaud / Muriel Bost Anne Marie ROUSSEL / 等多位
Micronutrients and cognitive impairment
微量元素和认知功能损伤的联系
Revue de Geriatrie – 04/2007
Monique Ferry / Anne-Marie Roussel
Mitochondrial production of reactive oxygen species and incidence of ageassociated lymphoma in OF1 mice: Effect of alternate-day fasting
线粒体能量产⽣和⽼⿏淋巴瘤在阶段型断⻝的研究
Mechanisms of Ageing and Development – 12/2005
Anne-Marie Roussel / Olivier Descamps / Jacqueline Riondel / Véronique Ducros
Alterations of antioxidant trace elements (Zn, Se, Cu) and related metallo-enzymes in plasma and tissues following burn injury in rats
⽤不同抗氧化元素和相关酶制剂对烧伤⽼⿏组织的研究
BURNS – 06/2005
D Agay / R.A. Anderson / C Sandre / Yves Chancerelle / Anne-Marie ROUSSEL
Influence of Short-Chain Fructo-Oligosaccharides (sc-FOS) on Absorption of Cu, Zn, and Se in Healthy Postmenopausal Women
短链低聚果糖对绝经期女性钙、锌和硒元素吸收的影响
Journal of the American College of Nutrition – 03/2005
Véronique Ducros / Anne-Marie Roussel 等多位
Antioxidant vitamin status in high exposure to oxidative stress in competitive athletes
⾼⽔平运动员的抗氧化元素状态研究
BRITISH JOURNAL OF NUTRITION -09/2004
Anne Marie Roussel / Anne-Sophie Rousseau 等多位
Effects of a combined micronutrient supplementation on maternal biological status and newborn anthropometrics measurements: A randomized double-blind, placebocontrolled trial in apparently healthy pregnant women
微量元素摄⼊对孕妇和新⽣⼉的⽣化变化的影响:一项对健康的孕妇中进行的随机双盲安慰剂对照试验
European Journal of Clinical Nutrition – 02/2004
Anne-Marie Roussel / Isabelle Hininger /等多位
No Antioxidant Effect of Combined HRT on LDL Oxidizability and Oxidative Stress Biomarkers in Treated Post-Menopausal Women
绝经期⼥性对氧化和抗氧化治疗的⽣化反应
Journal of the American College of Nutrition – 08/2002
Anne-Marie Roussel / Isabelle Bureau / 等多位
Beneficial effect of an antioxidant micronutrient-enriched food on DNA damage: experimental study in rats using a modified comet assay in total blood
抗氧化微量元素⻝物对DNA(基因)受损的研究 (⽼⿏⾎液研究试验)
IARC Scientific publication – 02/2002
Anne-Marie Roussel / Isabelle Hininger / 等多位
Trace mineral status in post menopausal women: Impact of hormonal replacement therapy
绝经期妇⼥荷尔蒙治疗微量元素跟踪
Journal of Trace Elements in Medicine and Biology – 02/2002
Anne-Marie Roussel / Isabelle Bureau / Richard A 等多位
Determinants of Blood Selenium Concentrations in France (SU VI MAX Study)
法国人⾎液中硒元素含量
Trace Elements in Man and Animals – 01/2002
Arnaud / Anne-Marie Roussel / Paul Preziosi 等多位
Oxidative Stress and Antioxidant Trace Element Status in Patients with Non-insulinDependent Diabetes
氧化问题以及抗氧化状态在⾮胰岛素糖尿病 – 01/2002
A.Kerkeni / Anne-Marie Roussel / Ali Othmane/ 等多位
Potential Antioxidant Effects of Zinc and Chromium Supplementation in People with Type 2 Diabetes Mellitus
锌和铬补充剂对2型糖尿病患者的潜在抗氧化作用
Journal of the American College of Nutrition – 07/2001
Richard A. Anderson / Anne-Marie Roussel / Nouri Zouari[…] / Abdelhamid Kerkeni
The SU.VI.MAX Study”: a primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers. Supplementation on VItamines et Minéraux Antioxydants
法国国家SU.VI.MAX研究:抗氧化、维生素、微量元素在⼼⾎管和癌症预防⽅⾯的应⽤
Food and Chemical Toxicology – 09/1999
Serge Hercberg / Paul Preziosi / Anne-Marie Roussel /等多位
Systemic Oxidative Stress and Cognitive Performance in the Population-Based EVA Study
氧化衰⽼和认知系统在衰⽼的应⽤
Free Radical Biology and Medicine – 05/1998
J Richard / Anne-Marie Roussel / C Bonithon-Kopp
Analyzed dietary intakes, plasma concentrations of zinc, copper, and selenium, and related antioxidant enzyme activities in hospitalized elderly women
住院年轻女性⾎浆中锌、铜、硒、其他微量元素,抗氧化含量和⻝物摄取之间的联系
Journal of the American College of Nutrition – 11/1996
A Schmuck / Anne Marie ROUSSEL / J Arnaud / Ducros
Vitamin Intakes (A, E, C, Carotenes) In A French Institution: Assessment By The Duplicate-Diet Method
法国人的维生素摄入量(A,E,C,胡萝卜素):采用重复饮食法进行评估
Annals of Nutrition and Metabolism – 02/1995
A Poupard / Anne-Marie Roussel / J Alary
Effect of acute zinc deficiency on insulin receptor binding in rat adipocytes
锌缺乏对于⽼⿏脂肪细胞中胰岛素的影响
Biological Trace Element Research – 05/1992
Marie-Jeanne Gomot / Patrice Faure/ Anne-Marie Roussel/等多位
Effects of varying dietary proteins on plasma lipids and rabbit platelet function
不⽤饮⻝和蛋⽩质摄取对⾎液脂肪和兔⾎⼩板活化因⼦的影响
Thrombosis Research- 03/1988
A Ravel / Anne-Marie Roussel / J Alary / J Laturaze
Nutritional value: Experimental analysis of effect on fat metabolism in rats
分析营养对⼩⽩⿏的代谢的影响
Jan 1980
Ravel / Anne-Marie Roussel / M. Boitard